5 Lactobacillus Casei Health Benefits


Lactobacillus Casei (L. Casei) operates most efficiently at a pH of 5.5 and is a type of good probiotic bacteria that may have benefits for gut health.

It is phylogenetically and phenotypically closely related to Lactobacillus Rhamnosus and Lactobacillus Paracasei but fundamentally is not the same.

In this guide I will be going over some of the potential health benefits of Lactobacillus Casei and Lactobacillus Casei Shirota based on the scientific studies that have been conducted. 


Colic is a condition where a baby cries for prolonged periods of time and can be distressing for parents. It is said to effect 1 in 4 infants and usually goes away with time. One such study proposed that colic could be caused by an imbalance in a babies gut bacteria. (1)

Another study hinted that a multi-strain breast fed colic probiotic formula containing L. casei versus a placebo should improvements for colic at the end of the study. It was carried out over 30 days with 50 infants and the formula contained a 1-Billion CFU count. (2)


If Lactobacillus Casei Shirota sounds familiar then it may be because it is the single strain used in a world famous drink called Yakult.

One study from 2003 tested 70 individuals with a Lactobacillus Casei Shirota probiotic drink versus a placebo drink.

They were given 65 ml per day and were examined weekly by Doctors in relation to their digestive symptoms.

At the end of the study 89% of participants claimed to have positive results in relation to their constipation. It is worth noting however that some of those in the placebo group also showed a positive reaction. (3)

Lactose Intolerance

At the end of this 4-week study there was a notable improvement in the symptoms of those with Lactose Intolerance and hydrogen production intake was reduced in the participants. 

The most fascinating part of this study was that the results continued for around 90 days after the participants had stopped taking the Lactobacillus Casei Shirota drink. (4)

Since the participants were able to digest milk better, L. Casei, could be useful for those who have to eat vegan yogurts even though they are not vegan. Another study tested Lactobacillus Rhamnosus on Children with Lactose Intolerance and the results were positive.


One studied carried out on Mice with IBD showed that Lactobacillus Casei taken orally helped with the inflammation from IBD and strengthened the Gut Barrier Function. The study was in depth and conclusive. It's definitely worth a read if you have the time. (5)


It's difficult to figure out what specific probiotic strain is Best For Diverticulitis. Some studies suggest Lactobacilli bacteria as a whole may be beneficial and Lactobacillus Reuteri in particular. (6)

Another study did attempt to study if Lactobacillus Casei Shirota in the form of a Yakult drink could be helpful for uncomplicated acute diverticulitis.

21 Participants not taking antibiotics with UAD were told to drink Yakult daily for one year. The number of attacks before taking Yakult was recorded and then this number was noted again 6-months and 12-months of drinking L. Casei Shirota daily.

The results showed that 14 out of 21 participants had their Diverticulitis symptoms improve. The study claimed that taking the L. Casei Shirota drink daily did reduce diverticulitis episodes. (7)

It has been noted previously that sugar content and fatty dairy can make Diverticulitis worse. Yakult may contain up to 8.8g of sugar which is a lot to consume daily but it does have 0g of fat. (8)

Side Effects & Warnings

Probiotics has difference effects on everyone based on their unique gut flora. Some people taking probiotics may experience side effects like Gas, Bloating, Diarrhea and more. If you experience any side effects you should consult with a Doctor asap and discontinue use. (6)

Lactobacillus Casei Bacteria Needs Prebiotic Fiber 


Avocados are a great Prebiotic

Many of the studies I listed in this Lactobacillus Casei guide did not include the use of prebiotic fiber. Prebiotic fiber is essential to feed the Lactobacillus Case and to in turn help it grow in your microbiome. You can get Prebiotics from supplements or natural foods like dark leafy greens, avocados and other vegetables.

Lactobacillus Casei Supplements and Foods


Pro 45 Has Lactobacillus Casei

There are many different supplements that contain Lactobacillus Casei bacteria. 1MD and Pro 45 are two good examples and as a bonus they also include important prebiotic fiber.


Yakult has Lactobacillus Casei Shirota

Yakult contains one single strain and that is Lactobacillus Casei Shirota, the strain that was used in some of the studies in this guide. The only downside to Yakult is that it does contain a large amount of sugar.


Some cheese like Mozzarella may have Lactobacillus Casei

Lactobacillus Casei produces lactic acid during fermentation and this give it's a fruity distinct taste that is useful for many types of cheese and some natural yogurts as well.

Closing Statement

Never use Lactobacillus Casei as a replacement to any prescribed medication from your Doctor and also consult a Doctor for any medical queries. This guide is NOT medical advice and I am not a Doctor.

The Lactobacillus Casei and Shirota strain looks promising for a wide range of health issues but more in depth studies may be needed. The use of Lactose Intolerance looks to be the most promising and user reports are also positive.

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