Bacillus Circulans Helped Inhibit Acne

Bacillus circulans is a type of probiotic bacteria that has been used in microbial fuel cell technology meaning it can produce electricity through fermentation.

Researchers from South Korea investigated whether B. Circulans could be used to ferment glucose and generate electricity, as well as to inhibit the growth of Acne. The results were amazing!

What Is Acne Vulgaris?

Acne is typically treated with antibiotics, which can inhibit C. acnes overgrowth and lipase activity. However, this type of treatment can also have side effects, such as promoting the emergence of antibiotic-resistant C. acnes strains and killing off other beneficial skin bacteria.

Alternative treatments, such as the use of probiotics, have been explored as a way to reduce C. acnes growth and alleviate inflammation without the negative side effects of antibiotics.

In this study, the researchers investigated the potential of Bacillus Circulans a honey probiotic, to ferment glucose and generate electricity, which could reduce C. acnes lipase activity and decrease inflammation.

How The Study Was Carried Out

This wasn't a simple placebo controlled study with the researchers instead examining whether Bacillus circulans (B. circulans), a type of bacteria commonly used in microbial fuel cell technology, could ferment glucose to generate electricity and inhibit the growth of human skin pathogens.

To test this, they first measured the electricity production of B. circulans by measuring the voltage difference and using a ferrozine assay in vitro. They then investigated the effects of B. circulans on the growth of the human skin pathogen Cutibacterium acnes (C. acnes) by injecting it intradermally into mice ears to induce an inflammatory response.

Bacillus Circulans Inhibited The Growth Of C. Acnes

These findings suggest that B. circulans can generate electrons that affect the growth of C. acnes through flavin-mediated electron transfer and alleviate the resulting inflammatory response.

Overall, the study suggests that probiotics can be used to generate electrical energy through carbon source fermentation and potentially help in the treatment of bacterial infections. If this was somehow replicated in a human study it could potentially help with acne.

Closing Thoughts: B. Circulans Helped With Acne

In this study I analysed, Bacillus circulans (B. circulans) was shown to be an effective electrogenic bacterium in microbial fuel cell (MFC) technology.

This means that that B. circulans can ferment glucose to generate electricity and reduce the effects of human skin pathogens, such as acne vulgaris.

The South Korean researchers found that the addition of glucose to the culture medium of B. circulans in vitro significantly inhibited the growth of C. acnes but this wasn't tested in humans.

When roseoflavin was added to the mix, the suppression was significantly reversed. This suggests that B. circulans affected the growth of C. acnes through the electrons generated by glucose fermentation and flavin-mediated electron transfer.

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